Professor Hutchison featured in the Times for attempting to grow replacement bone from a patient’s own stem cells in Britian.
The full article is available to read here.
Professor Hutchison featured in the Times for attempting to grow replacement bone from a patient’s own stem cells in Britian.
The full article is available to read here.
Following the surgical success of two full face transplants in China and France, Professor Iain Hutchison said that the twin successes would offer more encouragement for surgical teams considering carrying out their own operations.
Read the full article on the BBC here: http://news.bbc.co.uk/1/hi/health/7575364.stm
The story of Jose Mestre from Portugal attracted considerable media attention after Professor Iain Hutchison took part in a documentary looking at treatment options for him, which was featured on Discovery and Five.
The Saving Faces debate on The Face and Reconstruction, which took place on 4th March 2008 at the Southbank Centre attracted considerable media interest. The panel consisted of eminent surgeons, psychologists, and scientists, including Professor Bernard Devauchelle, who lead the world’s first face transplant operation in 2005. Prof Iain Hutchison, founder of Saving Faces, chaired the debate.
Faces come in all shapes, sizes and colours, but there are artificial standards that have been set throughout history for what constitutes attractiveness. Symmetry between the two facial sides is certainly highly regarded, while the balance of facial proportions described as the Hellenic norms is still prized today – as evidenced by the models in fashion magazines.
So what happens to our self-belief and society’s perception of us when our faces change through injury or disease? This depends not only on the severity of the damage but also on factors such as how the damage occurred, the age when it developed and the victim support network available. Older, married patients with fulfilling occupations cope better with these physical traumas than teenagers who rely on their peer group for emotional sustenance.
Our faces are also portals for breathing, smelling, seeing, eating and speech. So they are fundamentally important in our ability to perform vital social functions. The face is important in recognition and identifying people too.
The increasing importance of the face to self-esteem has resulted in a burgeoning desire for treatments to convert faces to the Hellenic norm and arrest the ravages of ageing. Emotional and financial success is often associated with youthful vigour rather than elderly experience.
We can think of the face as an underlying skeletal scaffold made up of highly complex bony architecture with air sinuses to lighten our heads so we don’t drag them along the floor. These air sinuses are also important in speech and breathing. Within these bones we have teeth, which hold our lips and cheeks out in an attractive fashion. Draped over this bone is skin with highly complicated three-dimensional patterns. Skin has different texture, thickness and hair-bearing capacity at various sites on the face.
Surgical advances have achieved the ability to mimic the face’s underlying bony landmarks, but we cannot use skin from other sites of the body to exactly mimic facial skin. Therefore the face transplant carried out by Professors Devauchelle and Testelin in 2005, replacing the skin of a patient’s nose, lips and cheek, was a major breakthrough in surgical reconstruction of the facial soft tissues. It captured the public imagination, not only because of the dramatic physical result but also because it suggested the possibility of great advances in cosmetic surgery. However, the public did not consider the immense risks of the immunosuppressant drug therapy necessary to prevent rejection of the transplant from a dead donor. These drugs cause muscle-wasting, bone loss and spotty skin, and increase the risks of malignant tumours developing. So there is no current role for face transplantation in cosmetic surgery.
Face transplants clearly have a role to play for severe burn victims, but they are not life-saving operations. Each patient must consider the risk-benefit ratio before embarking on such a dramatic course. There are also psychological effects caused by carrying around somebody else’s facial skin – for the patient, their family and the family of the person whose skin was donated.
Researchers are working on growing spare body parts from a patient’s own stem cells. The potential for “tissue engineering” is immense, because there is no need for immunosuppressants. This is still in the realm of science fiction, but could become reality within a decade. We have already seen growth of a patient’s skin cells in the laboratory and growth of a replacement lower jaw within the patient’s body using computer modelling and the patient’s stem cells. The future awaits, and face transplants may already be consigned to history.
[Reproduced from The Guardian. The full article: https://www.theguardian.com/commentisfree/2008/mar/04/sciencenews]
Facial reconstruction is making great advances, and may soon enter the realm of science fiction.
Professor Hutchison featured in an article in The Telegraph, titled “Fighting the curse of the face eating tumour”
Prof Iain Hutchison talks to Barbara Myers in a radio phone-in on oral health.
Reproduced from The Times. 25th February 2006.
Kelly Smith, 21, lives in Yorkshire. Aged 15, she had a rare form of cancer which necessitated the removal of one eye and some of the tissue around it.